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mcarbone@cc.hawaii.edu

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings

10 May: BAP1 Regulates IP3R3-mediated Ca2+ Flux to Mitochondria Suppressing Cell Transformation

Nature: Cell Death and Disease 2017

Flavia Novelli, PhD

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By Oak Park Pathology BAP1 Syndrome Gene X Interaction Genetic Research Therapeutic Approaches Uncategorized

23 Nov: BAP1 Forms a Trimer with HMGB1 and HDAC1 that Modulates Gene ×Environment Interaction with Asbestos

Proceedings of the National Academy of Sciences in the USA 2021

Angela-Bononi-Lab

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By Oak Park Pathology BAP1 Syndrome Gene X Interaction Genetic Research Therapeutic Approaches Uncategorized

14 Dec: Heterozygous Germline BLM Mutations Increase Susceptibility to Asbestos and Mesothelioma

Proceedings of the National Academy of Sciences in the USA 2020

cancer-center-xue-jiaming-lab-1

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By Oak Park Pathology Asbestos BAP1 Syndrome Gene X Interaction Genetic Research HMGB1

20 Oct: Asbestos Induces Mesothelial Cell Transformation via HMGB1-driven Autophagy

Proceedings of the National Academy of Sciences in the USA 2020

biological-mechanisms

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By Oak Park Pathology BAP1 Syndrome Genetic Research

20 Jul: Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer

Cancer Discovery 2020

Michele Carbone, MD, PhD

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Gene X Interaction Genetic Research Research Findings

02 Jun: Tumour Predisposition and Cancer Syndromes as Models to Study Gene–Environment Interactions

Nature Reviews Cancer 2020

translational-lung-cancer-research

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings Therapeutic Approaches

15 Apr: Mesothelioma: What We Know and What We Do Not Know in 2020

Translational Lung Cancer Research: Focused Issue

Image-7-9-19-at-10.20-AM

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By Oak Park Pathology Asbestos BAP1 Syndrome Environmental Carcinogenesis Genetic Research HMGB1 Research Findings Therapeutic Approaches

10 Jul: Mesothelioma: Scientific Clues for Prevention, Diagnosis, and Therapy

Ca: A Cancer Journal for Clinicians 2019

41419_2018_1206_Fig1

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By Oak Park Pathology BAP1 Syndrome Genetic Research Research Findings

12 Dec: BAP1 Regulates Different Mechanisms of Cell Death

Nature 2018

Carbone_Yang_Teams_2016

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By Oak Park Pathology BAP1 Syndrome Environmental Carcinogenesis Genetic Research Research Findings

08 Nov: A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of BAP1 and Other Germline Mutations

Journal of Clinical Oncology 2018

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